The 6th house is one of the triangle houses which deals with obstacles in life and it is placed in the 2nd house which is the house of wealth so in general it is not a good placement. But since both are artha kona, so if the 6th House Lord In 2nd House then it indicates that the native can earn a lot otherwise it is not good. If the lord of the 6th house is heavily aspected then the native may suffer from incurable disease and may die due to the disease. In simple words, this combination strengthens the maraka effects of the 2nd house.